Health advice built for your body
Standard health guidelines are built on population averages. Your genetics, your ancestry, and your body composition aren't average. Sirpi closes that gap.
The problem with “normal”
Clinical reference ranges — the numbers that determine whether your lab result is flagged or not — are derived from large population studies. Those studies skew heavily toward specific cohorts. The result: “normal” ranges that may not describe your body at all.
A South Asian patient with a “normal” HbA1c may already be pre-diabetic. An East Asian patient with a “normal” BMI may carry disproportionate visceral fat. An African-descent patient may have different baseline creatinine levels that affect kidney function interpretation. Every population has blind spots in the standard model.
Ancestry-aware calibration means interpreting your data through the lens that fits your body, not the one that was cheapest to research.
How Sirpi personalizes
Every piece of data you share — labs, genetics, body composition, daily habits — feeds into a model that's specific to you. Here's what that looks like:
Risk interpretation that fits your body
Standard lipid panels flag the same thresholds for everyone. But cardiovascular risk varies by ancestry, body composition, and metabolic history. Sirpi interprets markers like ApoB, Lp(a), and LDL particle counts in the context of who you are — not who the study cohort was.
Body composition beyond BMI
BMI was designed as a population statistic, not an individual diagnostic. Sirpi accounts for body-fat distribution patterns, visceral fat risk, and metabolic markers like HOMA-IR — calibrated to your baseline, not a generic chart.
Genetics linked to your bloodwork
A genetic variant in isolation is trivia. The same variant alongside your actual biomarker trends is actionable. Sirpi connects 130 variants across 10 themes to your lab results, so you see what your genetics mean for your body right now.
Every conversation, calibrated
Nutrition, sleep, activity, recovery — every coaching interaction inherits context about your ancestry, your lab trends, your genetics, and your goals. The advice adapts to you, not the other way around.
Where the calibration is deepest
Sirpi's ancestry-aware calibration started with South Asian health patterns — a population where the gap between standard guidelines and actual risk is among the widest and best-documented. This is where our calibration runs deepest today:
South Asian calibration
- Cardiovascular risk factors (ApoB, Lp(a), LDL-P, hs-CRP)
- Metabolic markers (HbA1c, fasting insulin, HOMA-IR)
- BMI and body composition interpretation
- Genetic variant frequencies and dietary context
- Cultural dietary patterns and food recognition
- Coaching context across nutrition, sleep, and recovery
Expanding to more populations
The principle — interpret health data through the lens of your body — is universal. The depth of calibration grows with the evidence base and our user community. South Asian is first because that's where the research gap is widest and where our founder saw it firsthand. More ancestry-specific calibration layers are in development, prioritized by where the divergence from standard guidelines is most clinically significant.
Meanwhile, everything else Sirpi does — the 173-biomarker extraction engine, genetic variant interpretation, food photo analysis, DEXA tracking, sleep and recovery coaching, wearable integration — works for everyone, today. Calibration is a layer that makes interpretation more precise. It's not a gate.
The full platform
Ancestry calibration is one layer. Here's everything Sirpi brings together:
173 biomarkers
Extracted from any lab PDF, trended over time
21 panels
Heart, metabolic, thyroid, hormones, iron, vitamins, and more
130 genetic variants
From 23andMe or AncestryDNA raw data
10 genetic themes
Each linked to your actual biomarker trends
DEXA analysis
Hologic, GE Lunar, and Norland scanners
AI food recognition
Photo-based, multi-cuisine, macro breakdown
Wearable sync
WHOOP, Oura, Apple Health
Daily coaching
Nutrition, sleep, activity, recovery
WhatsApp logging
Log meals and get coaching via chat